Human FGF19 is expressed during brain development and embryogenesis and is a high-affinity, heparin-dependent ligand for FGF receptor 4. Among FGF family members, human FGF19 is most closely related to murine FGF15 and chicken FGF19. Recombinant Human FGF19 is a non-glycosylated, 21.9 kDa protein that contains 195 amino acid residues.