Recombinant Human TNFRSF1A

A member of the TNFR superfamily, it is one of the major receptors for tumor necrosis factor-alpha (TNF_). Binding of either TNF-_ or TNF-_ to TNFRSF1A starts a signal transduction pathway that results in the activation of the transduction factor NF-_B, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis.