Recombinant Human CTGF

Secreted by vascular endothelial cells, CTGF is a regulatory protein that has been shown to stimulate the growth of chondrocytes, promote angiogenesis and mediate cell adhesion of fibroblasts and endothelial cells. The binding of CTGF to heparin induces cell migration and adhesion. Mature Human CTGF is a 38.0 kDa secreted protein that is comprised of four distinct structural domains (a) IGFBP N-terminal domain (b) VWFC domain (c) TSP type-I domain and (d) C-terminal CTCK domain. Recombinant Human CTGF is an 11.3 kDa protein monomeric protein that maps to the CTCK domain.